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2018年代表性论文
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1. Jingjing Han#, Jiaozhen Zhang#, Rongxiu Zhu, Yi Li, Yanan Qiao, Yun Gao, Xueyang Jin, Wang Chen, Jinchuan Zhou, and Hongxiang Lou*. Plagiochianins A and B, Two ent-2,3-seco-Aromadendrane Derivatives from the Liverwort Plagiochila duthianaOrganic Letters, 2018, 20(20): 6550-6553.

2. Yi Li, Rongxiu Zhu, Jiaozhen Zhang, Xueyi Wu, Tao Shen, Jinchuan Zhou, Yanan Qiao, Yun Gao, and Hongxiang Lou*. Clerodane diterpenoids from the Chinese liverwort Jamesoniella autumnalis and their anti-inflammatory activity. Phytochemistry, 2018, 154: 85–93.

3. Yanan Qiao, Hongbo Zheng, Lin Li, Jiaozhen Zhang, Yi Li, Siwen Li, Rongxiu Zhu, Jinchuan Zhou, Shengtian Zhao, Yuehua Jiang, Hongxiang Lou*, Terpenoids with vasorelaxant effects from the Chinese liverwort Scapania carinthiaca. Bioorganic & Medicinal Chemistry, 2018, 26: 4320–4328.

4. Jiaozhen Zhang, Yongjie Wang, Rongxiu Zhu, Yi Li, Yuelan Li, Yanan Qiao, Jinchuan Zhoud and Hongxiang Lou*.Cyperane and eudesmane-type sesquiterpenoids from Chinese liverwort and their anti-diabetic nephropathy potential. RSC Advances, 2018, 8: 39091–39097.

5. Yuelan Li, Rongxiu Zhu, Jiaozhen Zhang, Fei Xie, Xiaoning Wang, Ke Xu, Yanan Qiao, Zuntian Zhao, and Hongxiang Lou*. Ophiosphaerellins A-I, Polyketide-Derived Compounds from the Endolichenic Fungus Ophiosphaerella korrae. ACS Omega, 2018, 3: 176-180.

6. Ke Xu, Yun Gao, Yuelan Li, Fei Xie, Zuntian Zhao*, and Hongxiang Lou*. Cytotoxic pTerphenyls from the Endolichenic Fungus Floricola striata. Journal of Natural Products. 2018, 81: 2041-2049.

7. Jin TY, Li SQ, Jin CR, Shan H, Wang RM, Zhou MX, Li AL, Li LY, Hu SY, Shen T*, Xiang L*. Catecholic Isoquinolines from Portulaca oleracea L. and their anti-inflammatory and β2-adrenergic receptor agonist activity. Journal of Natural Products. 2018, 81: 768-777.

8. Hu SY, Zheng YN, Ding CB, Hao YW, Cui B, Xiang L*. Isolation and identification of components in the dihydroquercetin-rich extract from larch wood (Larix olgensis Henry). European Journal of Medicinal Plants, 2018, 24(2): 1-8.

9. Yuefang ZhouShanshan Wang, Hongxiang Lou, Peihong Fan*. Chemical constituents of hemp (Cannabis sativa L.) seed with potential anti-neuroinflammatory activity. Phytochemistry Letter, 2018, 23,57-61.

10. Yuefang Zhou, Shanshan Wang, Jianbo Ji, Hongxiang Lou, Peihong Fan*.  Hemp (Cannabis sativa L.) seed phenylpropionamides composition and effects on memory dysfunction and biomarkers of neuroinflammation induced by lipopolysaccharide in mice. ACS Omega, 2018, 3 (11), 15988–15995.

11. Shanshan Wang, Qian Luo, Peihong Fan*. Cannabisin F from Hemp (Cannabis sativa) Seed Suppresses Lipopolysaccharide-Induced Inflammatory Responses in BV2 Microglia as SIRT1 Modulator, International Journal of Molecular Sciences, 2019, 20, 507.

12. Ting Li, Shanshan Wang, Peihong Fan*, Hongxiang Lou. New coumarins and monoterpene galloylglycoside from the stem bark of Sapium baccatum. Fitoterapia, 2019, 134, 435-422.

13. Wenqiang Chang, Jun Liu, Ming Zhang, Hongzhuo Shi, Sha Zheng, Xueyang Jin, Yanhui Gao, Shuqi Wang, Aiguo Ji and Hongxiang Lou*. Efflux pump-mediated resistance to antifungal compounds can be prevented by conjugation with triphenylphosphonium cation. Nature communications, 2018, 9:5102.

14. Sha Zheng, Wenqiang Chang, Ming Zhang, Hongzhuo Shi, and Hongxiang Lou*. Chiloscyphenol a derived from chinese liverworts exerts fungicidal action by eliciting both mitochondrial dysfunction and plasma membrane destruction. Scientific Reports, 2018, 8(1): 326.

15. Ming Zhang, Wenqiang Chang, Hongzhuo Shi, Ying Li, Sha Zheng, Wei Li, and Hongxiang Lou*. Floricolin c elicits intracellular ros accumulation and disrupts mitochondria to exert fungicidal action. FEMS Yeast Research, 2018, 18(1) foy002.

16. Lin Li, Bin Sun, Yun Gao, Huanmin Niu, Huiqing Yuan*, Hongxiang Lou*. STAT3 contributes to lysosomal-mediated cell death in a novel derivative of riccardin D-treated breast cancer cells in association with TFEB. Biochemical Pharmacology. 2018, 150: 267-279.

17. Ming-Xing Zhou; Guo-Hui Li; Bin Sun; You-Wei Xu; Ai-Ling Li; Yan-Ru Li; Dong-Mei Ren; Xiao-Ning Wang; Xue-Sen Wen; Hong-Xiang Lou; Tao Shen. Identification of novel Nrf2 activators from Cinnamomum chartophyllum H.W. Li and their potential application of preventing oxidative insults in human lung epithelial cells, Redox Biology, 2018, 14: 154-163

18. Wen-Jing Yang ; Yan-Ru Li ; Hui Gao; Xue-Yi Wu; Xiao-Ling Wang; Xiao-Ning Wang; Lan Xiang; Dong-Mei Ren; Hong-Xiang Lou; Tao Shen. Protective effect of the ethanol extract from Ligusticum chuanxiong rhizome against streptozotocin–induced diabetic nephropathy in mice, Journal of Ethnopharmacology, 2018, 227: 166-175.

19. Yan-Ru Li ; Guo-Hui Li; Lin Sun; Lin Li; Yue Liu; De-Gang Kong; Shu-QiWang; Dong-Mei Ren; Xiao-Ning Wang; Hong-Xiang Lou; Tao Shen* Ingredients from Litsea garrettii as potential preventive agents against oxidative insult and inflammatory response. Oxidative Medicine and Cellular Longevity, 2018, 2018: 7616852.

20. Yan-Ru Li ; Chun-Sheng Fu; Wen-Jing Yang; Xiao-Ling Wang; Dan Feng; Xiao-Ning Wang; Dong-Mei Ren; Hong-Xiang Lou; Tao Shen, Investigation of constituents from Cinnamomum camphora (L.) J. Presl and evaluation of theiranti-inflammatory properties in lipopolysaccharide stimulated RAW 264.7 macrophages, Journal of Ethnopharmacology, 2018, 221: 37-47.

21. Yan-Ru Li ; Guo-Hui Li; Ming-Xing Zhou; Lan Xiang; Dong-Mei Ren; Hong-Xiang Lou; Xiao-Ning Wang; Tao Shen, Discovery of natural flavonoids as activators of Nrf2-mediated defense system: structure-activity relationship and inhibition of intracellular oxidative insults, Bioorganic & Medicinal Chemistry, 2018, 26: 5140-5150.

22. Ai-Ling Li ; Bang-Jiao Chen; Guo-Hui Li; Ming-Xing Zhou; Yan-Ru Li; Dong-Mei Ren; Hong-Xiang Lou; Xiao-Ning Wang, Tao Shen. Physalis alkekengi L. var. franchetii (Mast.) Makino: an ethnomedical, phytochemical and pharmacological review, Journal of Ethnopharmacology, 2018, 210: 260-274.

23. Hongbo Zheng, Yifeng Wu, Bin Sun, Chuanle Cheng, Yanan Qiao, Yuehua Jiang, Shengtian Zhao, Zhiyu Xie, Jing Tan, Hongxiang Lou. Discovery of Furyl/Thienyl β-carboline Derivatives as Potent and Selective PDE5 Inhibitors with Excellent Vasorelaxant Effect. Eur. J. Med. Chem. 2018, 158, 767-780.

24. Hongbo Zheng, Lin Li, Bin Sun, Yun Gao, Wei Song, Xiaoyu Zhao, Yanhui Gao, Zhiyu Xie, Nianzhao Zhang, Jianbo Ji, Huiqing Yuan, HongxiangLou. Design and Synthesis of Furyl/Thineyl Pyrroloquinolones Based on Natural Alkaloid Perlolyrine, Lead to the Discovery of Potent and Selective PDE5 Inhibitors. Eur. J. Med. Chem. 2018, 150, 30–38.

25. Yu, H. N., Liu, X. Y., Gao, S., Sun, B., Zheng, H. B., Ji, M., Cheng, A. X., & Lou, H. X. (2018). Structural and biochemical characterization of the plant type III polyketide synthases of the liverwort Marchantia paleacea. Plant Physiology and Biochemistry125, 95-105.

26. Wu, Y. F., Zhao, Y., Liu, X. Y., Gao, S., Cheng, A. X., & Lou, H. X. (2018). A bHLH Transcription Factor Regulates Bisbibenzyl Biosynthesis in the Liverwort Plagiochasma appendiculatumPlant and Cell Physiology59(6), 1187-1199.

27. Wu, Y. F., Zheng, H. B., Liu, X. Y., Cheng, A. X., & Lou, H. X. (2018). Molecular Diversity of Alkenal Double Bond Reductases in the Liverwort Marchantia paleaceaMolecules23(7), 1630.

28. Wu, Y. F., Zhao, Y., Liu, X. Y., Gao, S., Cheng, A. X., & Lou, H. X. (2018). Isolation and functional characterization of hydroxycinnamoyltransferases from the liverworts Plagiochasma appendiculatum and Marchantia paleaceaPlant Physiology and Biochemistry.129, 400-410.

29. Liu, X. Y., Wang, P. P., Wu, Y. F., Cheng, A. X., & Lou, H. X. (2018). Cloning and Functional Characterization of Two 4-Coumarate: CoA Ligase Genes from Selaginella moellendorffii. Molecules23(3), 595.

30. Zhongyue Li, Deyu Zhu, Yuemao Shen* (2018). Discovery of novel bioactive natural products driven by genome mining. Drug Discov. Ther. 12, 318–328.

31. Yuemao Shen*, Duozhi Chen (2018). An explorer of chemical biology of plant natural products in Southwest China, Xiaojiang Hao. Nat. Prod. Bioprospect. 8, 217–226.

32. Yaoyao Li, Haoxin Wang, Yan Liu, Yujie Jiao, Shanren Li, Yuemao Shen*, Liangcheng Du* (2018). Biosynthesis of the polycyclic system in the antifungal HSAF and analogues from Lysobacter enzymogenes. Angew. Chem. Int. Ed. 57, 6221–6225.

33. Xingkang Wu, Zhenyu Li, Yuemao Shen* (2018). The small molecule CS1 inhibits mitosis and sister chromatid resolution in HeLa cells. BBA – Gen. Subjects 1862, 1134–1147.

34. Xingkang Wu, Yuemao Shen* (2018). PMN inhibits colorectal cancer cells through inducing mitotic arrest and p53-dependent apoptosis via the inhibition of tubulin polymerization. Biochem. Biophys. Res. Commun. 499 (4), 927–933.

35. Chuanpeng Liang, Xingkang Wu, Zhenyu Li, Jing Zhu, Chunhua Lu, Yuemao Shen* (2018). Design, synthesis and pharmacological evaluation of N-(5-chloro-2,4-dihydroxybenzoyl)-(R)-N-arylmethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxamides as potent Hsp90 inhibitors. Eur. J. Med. Chem. 143, 85–96.

36. Wei Xie, Wei Zhang, Mingwei Sun, Chunhua Lu, Yuemao Shen* (2018). Deacetylmycoepoxydiene is an agonist of Rac1, and simultaneously induces autophagy and apoptosis. Appl. Microbiol. Biotechnol. 102, 5965–5975.

37. Xiaomei Li, Xingkang Wu, Jing Zhu, Yuemao Shen* (2018). Amexanthomycins A–J, pentangular polyphenols produced by Amycolatopsis mediterranei S699∆rifA. Appl. Microbiol. Biotechnol. 102, 689–702.

38. Tianhong Li, Dongdong Zhang, Thaung Naing Oo, Myint Myint San, Aye Mya Mon, Pyae Phyo Hein, Yuehu Wang, Chunhua Lu*, Xuefei Yang* (2018). Investigation on the antibacterial and anti-T3SS activity of traditional Myanmar medicinal plants. Evidence-based Complementary and Alternative Medicine 2018, 113.

39. Jianxiong Wang, Wen Li, Haoxin Wang, Chunhua Lu* (2018). Pentaketide ansamycin microansamycins A−I from Micromonospora sp. reveal diverse post-PKS modifications. Org. Lett. 20, 1058−1061.

40. Yan Liu, Haoxin Wang, Rentai Song, Jining Chen, Tianhong Li, Yaoyao Li*,  Liangcheng Du, Yuemao Shen (2018).Targeted discovery and combinatorial biosynthesis of polycyclic tetramate macrolactam combamides A-E. Org Lett. 20, 35043508.

41. Jianxiong Wang+, Xiaoman Li+, Chunhua Lu,* and Yuemao Shen2018. Diversity of polyketide chains achieved by deleting the tailoring genes in the biosynthesis of ansatrienins. Chem. Bio. Chem, 19, 256-262.

42. Feifei Wei, Wen Li, Rentai Song and Yuemao Shen* (2018). Trinulactones AD, new dinorsesterterpenoids from Streptomyces sp. S006. Nat. Prod. Commun. 13(11): 1433-1436.

43. Yanrong Shi, Juanli Zhang, Xiuyu Tian, Xingkang Wu, Tianhong Li, Chunhua Lu, Yuemao Shen* (2019). Isolation of 11,12-seco-rifamycin W derivatives reveals a cleavage pattern of the rifamycin ansa chain. Org. Lett. 21, 900903.

44. Yang Wu, Juanli Zhang, Wenxing Xiang, Mingzi Wang, Chunhua Lu* (2019). Two New Lipodepsipeptides from the Endophytic Fungus Colletotrichum aotearoa Y41. Rec. Nat. Prod. 13(3):199-204.

45. Jining Chen, Xingkang Wu, Chunhua Lu**, Xun Li* (2019). E17 exerts anti-tumor activity through inhibiting topo II-mediatedchromosomes condensation in CRC cells. Biochem. Biophy. Res. Commun. https://doi.org/10.1016/j.bbrc.2019.04.002.

 

 
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